Ongoing Projects

Molecular Imaging

Molecular imaging is a rapidly evolving field in medical science that uses various imaging techniques to visualize and analyze the biochemical processes and molecular pathways of living organisms. It provides a non-invasive way to study the molecular and cellular mechanisms of diseases. In our lab, we focus on developing and using innovative tracers for cancer diagnosis and staging. 

Translational Medicine 

Translational medicine refers to the process of translating basic research discoveries into clinical applications that can benefit patients. It involves a multidisciplinary approach that bridges the gap between laboratory research and clinical practice, with the goal of developing new treatments and improving patient outcomes. In our lab, we conduct both preclinical and clinical research with the aim to achieve translatable clinical impact. 

Novel Radiopharmaceuticals

Currently available radiotracers have limitations in terms of specificity, sensitivity, and accessibility, making it difficult to accurately detect and treat certain types of cancer. Developing new radiotracers that target specific biomarkers or molecular pathways will enable earlier and more accurate diagnosis, as well as better monitoring of treatment response. This will ultimately lead to better patient outcomes and a more efficient use of healthcare resources. Furthermore, new radiotracers could help address the rising incidence of cancer worldwide, particularly in developing countries where access to advanced medical technology is limited.

Clinical Trials

• Long-Term Tolerability, Efficacy and Survival of Peptide Receptor Radionuclide Therapy (PRRT) in Metastatic Neuroendocrine Tumors of Unknown Primary (CUP-NETs)

• Long-term Nephrotoxicity after PRRT: Mythos or Reality?

• Norepinephrine transporter targeted PET/CT with 18F-MFBG in patients with neural crest tumors

Preclinical Studies

• Modification of FAPI probes

• Discovery of novel albumin binders through DEL and computational methods

Advancing Magnetic Resonance Imaging for Non-Invasive Disease Monitoring and Therapeutic Visualization​

Our research group focuses on optimizing the magnetic and imaging properties of inorganic nanoprobes, representative of Magnetic Resonance Imaging (MRI) techniques. These nanoprobes are chemically synthesized to enhance their magnetic response, thereby improving the sensitivity and specificity of MRI. By harnessing the capabilities of these optimized nanoprobes, our aim is to enable non-invasive disease monitoring and visualization for enhanced diagnosis and treatment. Additionally, we are developing the novel drug delivery system based on dynamic nano assembly, which can be modulated by the physiological environment. This system holds great potential for targeted therapies in major diseases such as malignant tumors.